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dc.contributor.authorSingh N.D.-
dc.contributor.authorSharma A.K.-
dc.contributor.authorPatil R.D.-
dc.contributor.authorRahman S.-
dc.contributor.authorLeishangthem G.D.-
dc.contributor.authorKumar M.-
dc.identifier.citationIndian Journal of Experimental Biology (2014), 52(2): 159-167-
dc.description.abstractCitrinin is the one of the well-known mycotoxins, which is possibly spread all over the world. The graded doses of citrinin (1, 3 and 5 ppm CIT in feed) in female Wistar rats 10 weeks prior to mating, during mating and during organogenesis resulted in resorptions and post implantation losses, decreased fetal body weights and crown-rump lengths in fetuses of all groups. Various developmental anomalies recorded in fetuses of treated rats included gross (wrist drop, curled tail, stretched forelimb, subcutaneous haematoma), skeletal (incomplete ossification of skull bones, incomplete fusion of vertebral bodies, complete and partial agenesis of sternaebrae, metacarpals, metatarsals and phalanges, fused ribs and swing out ribs) and visceral (internal and external hydrocephalus, cerebellar hypoplasia, microphthalmia, roundening of heart, contracted kidneys, dilated renal pelvis and cryptorchid testes). The results suggest that CIT has adverse effects on fetal development which may be due to the longer bioavailability of citrinin in the animals.-
dc.relation.ispartofIndian Journal of Experimental Biology-
dc.titleEffect of feeding graded doses of Citrinin on clinical and teratology in female Wistar rats-
dc.affiliationSingh, N.D., Division of Pathology Indian Veterinary Research Institute, Izatnagar 243 122, India-
dc.affiliationSharma, A.K., Division of Pathology Indian Veterinary Research Institute, Izatnagar 243 122, India-
dc.affiliationPatil, R.D., Department of Veterinary Pathology, College of Veterinary Science, CSKHPKVV, Palampur 176 062, India-
dc.affiliationRahman, S., Department of Veterinary Pathology, College of Veterinary Science, SKUAST, Jammu 181 102, India-
dc.affiliationLeishangthem, G.D., Department of Pathology, All India Institute of Medical Sciences, New Delhi 110 029, India-
dc.affiliationKumar, M., High Security Animal Disease Laboratory, Bhopal 462 021, India-
dc.description.correspondingauthorSingh, N. D.; College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana 144 002, India; email:
Appears in Collections:Journal Publications [MS]

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