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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/8278
Title: Effect of Oxidative Damage on Charge and Spin Transport in DNA
Authors: Mishra S.
Poonia, Vishvendra Singh
Fontanesi C.
Naaman R.
Fleming A.M.
Burrows C.J.
Published in: Journal of the American Chemical Society
Abstract: A Hall device was used for measuring spin polarization on electrons that are either reorganized within the molecules or transmitted through the self-assembled monolayers of DNA adsorbed on the device surface. We were able to observe spin-dependent charge polarization and charge transport through double-stranded DNA of various lengths and through double-stranded DNA containing oxidative damage. We found enhancement in the spin-dependent transport through oxidatively damaged DNA. This phenomenon can be rationalized either by assuming that the damaged DNA is characterized by a higher barrier for conduction or by charge transfer through the DNA being conducted through at least two channels, one involves the bases and is highly conductive but less spin selective, while the other pathway is mainly through the ribophosphate backbone and it is the minor one in terms of charge transmission efficiency, but it is highly spin selective. © 2018 American Chemical Society.
Citation: Journal of the American Chemical Society (2019), 141(1): 123-126
URI: https://doi.org/10.1021/jacs.8b12014
http://repository.iitr.ac.in/handle/123456789/8278
Issue Date: 2019
Publisher: American Chemical Society
ISSN: 27863
Author Scopus IDs: 55463281500
56674806200
55923159700
7005842943
24491624300
7202089008
Author Affiliations: Mishra, S., Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, 76100, Israel
Poonia, V.S., Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, 76100, Israel
Fontanesi, C., Dip. di Ingegneria, DIEF, MO26, Via P. Vivarelli 10, Modena, 41125, Italy
Naaman, R., Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, 76100, Israel
Fleming, A.M., Department of Chemistry, University of Utah, 315 S. 1400 East, Salt Lake City, UT 84112-0850, United States
Burrows, C.J., Department of Chemistry, University of Utah, 315 S. 1400 East, Salt Lake City, UT 84112-0850, United States
Funding Details: R.N. acknowledges the support by the Israel Science Foundation and by the Israel−China program ISF-NSFC Grant No. 2475/17, and the John Templeton Foundation. C.J.B. thanks the U.S. National Science foundation for support via grant no. CHE-1808745.
Corresponding Author: Naaman, R.; Department of Chemical and Biological Physics, Weizmann Institute of ScienceIsrael; email: ron.naaman@weizmann.ac.il
Appears in Collections:Journal Publications [ECE]

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