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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/4169
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dc.contributor.authorSingh R.-
dc.contributor.authorTyagi S.-
dc.contributor.authorSingh S.-
dc.contributor.authorSingh S.M.-
dc.contributor.authorSingh U.P.-
dc.date.accessioned2020-10-06T14:32:09Z-
dc.date.available2020-10-06T14:32:09Z-
dc.date.issued2002-
dc.identifier.citationSynthesis and Reactivity in Inorganic and Metal-Organic Chemistry (2002), 32(5): 853-872-
dc.identifier.issn945714-
dc.identifier.urihttps://doi.org/10.1081/SIM-120005607-
dc.identifier.urihttp://repository.iitr.ac.in/handle/123456789/4169-
dc.description.abstractMixed-ligand complexes of Co(II), Ni(Il), Cu(II), Zn(II) and Cd(II) with adenine as primary ligand and 5-bromouracil as secondary ligand were prepared in aqueous ethanol solution at pH of about 7 and subjected to a screening system of Dalton's Lymphoma (DL) tumor cells in vitro for the evaluation of viability, 3 H-thymidine incorporation and induction of apoptosis in tumor cells. The isolated complexes were characterized by various physico-chemical methods. Solution studies were performed pH-metrically for the interaction of the above metal ions with adenine and 5-bromouracil separately (binary) and in the presence of each other (ternary) at 25 ± 0.1°C temperature and a constant ionic strength of 0.1 M NaNO 3 in aqueous solution.-
dc.language.isoen_US-
dc.relation.ispartofSynthesis and Reactivity in Inorganic and Metal-Organic Chemistry-
dc.titleSolid, solution, and antitumor activity studies of mixed-ligand complexes with adenine-5-bromouracil base pair-
dc.typeArticle-
dc.scopusid57198437313-
dc.scopusid7202432794-
dc.scopusid57206711794-
dc.scopusid7406398328-
dc.scopusid57203181883-
dc.affiliationSingh, R., Department of Chemistry, Indian Institute of Technology(formerly University of Roorkee), Roorkee, 247 667, India-
dc.affiliationTyagi, S., Department of Chemistry, Indian Institute of Technology(formerly University of Roorkee), Roorkee, 247 667, India-
dc.affiliationSingh, S., Department of Chemistry and, Banaras Hindu University, Varanasi, 221 005, India-
dc.affiliationSingh, S.M., Department of Chemistry, Indian Institute of Technology(formerly University of Roorkee), Roorkee, 247 667, India-
dc.affiliationSingh, U.P., Department of Chemistry, Indian Institute of Technology(formerly University of Roorkee), Roorkee, 247 667, India-
dc.description.fundingWe are thankful to University Grant Commission, New Delhi for financial assistance.-
dc.description.correspondingauthorSingh, U.P.; Department of Chemistry, Indian Institute of Technology, Roorkee 247 667, India; email: udaipfcy@rurkiu.ernet.in-
Appears in Collections:Journal Publications [CY]

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