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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/3748
Title: Synthesis, characterization and bactericidal activity of silica/silver core–shell nanoparticles
Authors: Devi P.
Patil S.D.
Jeevanandam P.
Navani N.K.
Singla M.L.
Published in: Journal of Materials Science: Materials in Medicine
Abstract: Silica/silver core–shell nanoparticles (NPs) were synthesized by coating silver NPs on silica core particles (size ~300 ± 10 nm) via electro less reduction method. The core–shell NPs were characterized for their structural, morphological, compositional and optical behavior using X-ray diffraction, scanning electron microscopy, energy dispersive X-ray analysis and UV–Visible spectroscopy, respectively. The size (16–35 nm) and loaded amount of silver NPs on the silica core were found to be dependent upon reaction time and activation method of silica. The bactericidal activity of the NPs was tested by broth micro dilution method against both Bacillus subtilis (gram positive) and Escherichia coli ATCC25922 (gram negative) bacterium. The bactericidal activity of silica/silver core–shell NPS is more against E. coli ATCC25922, when compared to B. subtilis. The minimal inhibitory concentration of the core–shell NPs ranged from 7.8 to 250 μg/mL and is found to be dependent upon the amount of silver on silica, the core. These results suggest that silica/silver core–shell NPs can be utilized as a strong substitutional candidate to control pathogenic bacterium, which are otherwise resistant to antibiotics, making them applicable in diverse medical devices. © 2014, Springer Science+Business Media New York.
Citation: Journal of Materials Science: Materials in Medicine (2014), 25(5): 1267-1273
URI: https://doi.org/10.1007/s10856-014-5165-9
http://repository.iitr.ac.in/handle/123456789/3748
Issue Date: 2014
Publisher: Springer New York LLC
ISSN: 9574530
Author Scopus IDs: 36609995600
55614242900
6603602593
6507073924
6601963859
Author Affiliations: Devi, P., Academy of Scientific and Innovative Research, Central Scientific Instruments Organisation, Sector 30 C, Chandigarh, 160030, India
Patil, S.D., Indian Institute of Technology Roorkee, Roorkee, Uttarakhand 247667, India
Jeevanandam, P., Indian Institute of Technology Roorkee, Roorkee, Uttarakhand 247667, India
Navani, N.K., Indian Institute of Technology Roorkee, Roorkee, Uttarakhand 247667, India
Singla, M.L., Academy of Scientific and Innovative Research, Central Scientific Instruments Organisation, Sector 30 C, Chandigarh, 160030, India
Corresponding Author: Singla, M.L.; Academy of Scientific and Innovative Research, Central Scientific Instruments Organisation, Sector 30 C, India; email: singla_csio@yahoo.com
Appears in Collections:Journal Publications [CY]

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