http://repository.iitr.ac.in/handle/123456789/3514| Title: | Structural identification and cytotoxic activity of a polysaccharide from the fruits of Lagenaria siceraria (Lau) |
| Authors: | Ghosh, Kaushik Chandra K. Ojha A.K. Sarkar S. Islam S.S. |
| Published in: | Carbohydrate Research |
| Abstract: | A water-soluble polysaccharide, isolated from fruiting bodies of Lagenaria siceraria, is composed of methyl-α-d-galacturonate, 3-O-acetyl methyl-α-d-galacturonate, and β-d-galactose in a ratio of nearly 1:1:1. Compositional analysis, methylation analysis, periodate oxidation, and NMR studies (1H, 13C, 2D-COSY, TOCSY, NOESY, HMQC, and HMBC) revealed the presence of the following repeating unit in the polysaccharide: {A figure is presented}. This polysaccharide showed cytotoxic activity in vitro against human breast adenocarcinoma cell line (MCF-7). © 2009 Elsevier Ltd. All rights reserved. |
| Citation: | Carbohydrate Research (2009), 344(5): 693-698 |
| URI: | https://doi.org/10.1016/j.carres.2009.01.012 http://repository.iitr.ac.in/handle/123456789/3514 |
| Issue Date: | 2009 |
| Keywords: | Adenocarcinoma cell line (MCF-7) Lagenaria siceraria NMR spectroscopy Polysaccharide Structure |
| ISSN: | 86215 |
| Author Scopus IDs: | 57204513823 16030753900 22234622800 25936752600 7202012813 |
| Author Affiliations: | Ghosh, K., Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India Chandra, K., Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India Ojha, A.K., Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India Sarkar, S., School of Medical Science and Technology, Indian Institute of Technology, Kharagpur, 721 302 West Bengal, India Islam, S.S., Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India |
| Corresponding Author: | Islam, S.S.; Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, 721 102 West Bengal, India; email: sirajul_1999@yahoo.com |
| Appears in Collections: | Journal Publications [CY] |
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