http://repository.iitr.ac.in/handle/123456789/3453| Title: | Ru-Catalyzed One-Pot Diannulation of Heteroaryls: Direct Access to π-Conjugated Polycyclic Amides |
| Authors: | Shankar M. Ghosh, Kaushik Mukherjee K. Rit R.K. Sahoo A.K. |
| Published in: | Organic Letters |
| Abstract: | A novel Ru-catalyzed oxidative double annulation of heteroarenes with symmetrical and unsymmetrical alkynes is reported. A general method for the unsymmetrical annulation of heteroarenes with two distinct alkynes is showcased for the first time. Methylphenyl sulfoximine (MPS) plays an important role in the annulations of heteroarenes and allows the construction of structurally complex π-conjugated heteroarene-fused polycyclic amide skeletons via the formation of multiple C–C and C–N bonds in a single operation. The reaction exhibits excellent substrate scope and tolerates a wide range of functional groups. |
| Citation: | Organic Letters (2016), 18(24): 6416-6419 |
| URI: | https://doi.org/10.1021/acs.orglett.6b03314 http://repository.iitr.ac.in/handle/123456789/3453 |
| Issue Date: | 2016 |
| Publisher: | American Chemical Society |
| ISSN: | 15237060 |
| Author Scopus IDs: | 56245183200 57204513823 57209542702 55191583500 55658057152 |
| Author Affiliations: | Shankar, M., School of Chemistry, University of Hyderabad, Hyderabad, 500046, India Ghosh, K., School of Chemistry, University of Hyderabad, Hyderabad, 500046, India Mukherjee, K., School of Chemistry, University of Hyderabad, Hyderabad, 500046, India Rit, R.K., School of Chemistry, University of Hyderabad, Hyderabad, 500046, India Sahoo, A.K., School of Chemistry, University of Hyderabad, Hyderabad, 500046, India |
| Funding Details: | This research was supported by CSIR (02/(0155)/13/EMR-II). M.S., K.G., K.M., and R.K.R. thank CSIR, India, for a fellowship. We thank Navendu Mondal and Mou Mandal (University of Hyderabad) for fluorescence measurement and helpful discussions |
| Corresponding Author: | Sahoo, A.K.; School of Chemistry, University of HyderabadIndia; email: akhilchemistry12@gmail.com |
| Appears in Collections: | Journal Publications [CY] |
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