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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/3059
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dc.contributor.authorBanerjee S.-
dc.contributor.authorGnanamani E.-
dc.contributor.authorLynch S.R.-
dc.contributor.authorZuñiga F.Z.-
dc.contributor.authorJiménez-Vargas J.M.-
dc.contributor.authorPossani L.D.-
dc.contributor.authorZare R.N.-
dc.date.accessioned2020-10-06T14:25:37Z-
dc.date.available2020-10-06T14:25:37Z-
dc.date.issued2018-
dc.identifier.citationJournal of Natural Products (2018), 81(8): 1899-1904-
dc.identifier.issn1633864-
dc.identifier.other30028606-
dc.identifier.urihttps://doi.org/10.1021/acs.jnatprod.8b00527-
dc.identifier.urihttp://repository.iitr.ac.in/handle/123456789/3059-
dc.description.abstractWhile most scorpion venom components identified in the past are peptidic or proteinic in nature, we report here a new alkaloid isolated from the venom of the Mexican scorpion Megacormus gertschi. Nuclear magnetic resonance and mass spectrometric investigations elucidate the structure of the alkaloid as (Z)-N-(2-(1H-imidazol-4-yl)ethyl)-3-(4-hydroxy-3-methoxyphenyl)-2-methoxyacrylamide (1). A chemical method of synthesizing this alkaloid is also described. Although abundant in venom, the above alkaloid was not found to have insecticidal activity. Structural analysis suggests that this venom alkaloid might be of potential interest for evaluating its medicinal effect. Copyright © 2018 American Chemical Society and American Society of Pharmacognosy.-
dc.language.isoen_US-
dc.publisherAmerican Chemical Society-
dc.relation.ispartofJournal of Natural Products-
dc.titleAn Alkaloid from Scorpion Venom: Chemical Structure and Synthesis-
dc.typeArticle-
dc.scopusid37080201400-
dc.scopusid35319775800-
dc.scopusid56709241400-
dc.scopusid57203658531-
dc.scopusid36170674200-
dc.scopusid56013752900-
dc.scopusid35355951800-
dc.affiliationBanerjee, S., Department of Chemistry, Stanford University, Stanford, CA 94305, United States, Indian Institute of Science Education and Research Tirupati, Karakambadi Road, Tirupati, 517507, India-
dc.affiliationGnanamani, E., Department of Chemistry, Stanford University, Stanford, CA 94305, United States-
dc.affiliationLynch, S.R., Department of Chemistry, Stanford University, Stanford, CA 94305, United States-
dc.affiliationZuñiga, F.Z., Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autonoma de Mexico, Avenida Universidad, 2001, Apartado Postal 510-3, Cuernavaca, Morelos, 62210, Mexico-
dc.affiliationJiménez-Vargas, J.M., Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autonoma de Mexico, Avenida Universidad, 2001, Apartado Postal 510-3, Cuernavaca, Morelos, 62210, Mexico-
dc.affiliationPossani, L.D., Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autonoma de Mexico, Avenida Universidad, 2001, Apartado Postal 510-3, Cuernavaca, Morelos, 62210, Mexico-
dc.affiliationZare, R.N., Department of Chemistry, Stanford University, Stanford, CA 94305, United States-
dc.description.correspondingauthorZare, R.N.; Department of Chemistry, Stanford UniversityUnited States; email: zare@stanford.edu-
Appears in Collections:Journal Publications [CY]

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