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Title: Comparative assessment of different versions of axial and centrifugal LVADs: A review
Authors: Kannojiya V.
Das, Arup Kumar
Das P.K.
Published in: Artificial Organs
Abstract: Continuous-flow left ventricular assist devices (LVADs) have gained tremendous acceptance for the treatment of end-stage heart failure patients. Among different versions, axial flow and centrifugal flow LVADs have shown remarkable potential for clinical implants. It is also very crucial to know which device serves its purpose better to treat heart failure patients. A thorough comparison of axial and centrifugal LVADs, which may guide doctors in deciding before the implant, still lacks in the literature. In this work, an assessment of axial and centrifugal LVADs has been made to suggest a better device by comparing their engineering, clinical, and technological development of design aspects. Hydrodynamic and hemodynamic aspects for both types of pumps are discussed along with their biocompatibility, bearing types, and sizes. It has been observed numerically that centrifugal LVADs perform better over axial LVADs in every engineering aspect like higher hydraulic efficiency, better characteristics curve, lesser power intake, and also lesser blood damage. However, the clinical outcomes suggest that centrifugal LVADs experience higher events of infections, renal, and respiratory dysfunction. In contrast, axial LVADs encountered higher bleeding and cardiac arrhythmia. Moreover, recent technological developments suggested that magnetic type bearings along with biocompatible coating improve the life of LVADs. © 2021 International Center for Artificial Organs and Transplantation and Wiley Periodicals LLC.
Citation: Artificial Organs, 45(7): 665-681
Issue Date: 2021
Publisher: John Wiley and Sons Inc
Keywords: axial
clinical events
left ventricular assist device
ISSN: 0160564X
Author Scopus IDs: 57201503183
Author Affiliations: Kannojiya, V., Mechanical and Industrial Engineering Department, IIT Roorkee, Roorkee, India
Das, A.K., Mechanical and Industrial Engineering Department, IIT Roorkee, Roorkee, India
Das, P.K., Department of Mechanical Engineering, IIT Kharagpur, Kharagpur, India
Funding Details: This research work was supported by Ministry of Human Resource Development (MHRD) and Indian Council of Medical Research (ICMR) under the IMPRINT scheme (award number 3-18/2015-TSI). Indian Council of Medical Research, ICMR: 3-18/2015-TSI; Ministry of Education, India, MoE
Corresponding Author: Das, A.K.; Mechanical and Industrial Engineering Department, India; email:
Appears in Collections:Journal Publications [ME]

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