http://repository.iitr.ac.in/handle/123456789/2261| Title: | Novel magnetic antimicrobial nanocomposites for bone tissue engineering applications |
| Authors: | Bhowmick A. Saha A. Pramanik N. Banerjee S. Das M. Kundu, Patit Paban |
| Published in: | RSC Advances |
| Abstract: | In the present study, we demonstrate the fabrication of novel bone-like magnetic nanocomposites by the blending of chitosan, polymethylmethacrylate-co-2-hydroxyethylmethacrylate, and nano-hydroxyapatite-Fe3O4. The hybrid nanomaterials were thoroughly characterized by Fourier transform infrared spectroscopy, powder X-ray diffraction and field emission scanning electron microscopy. The magnetic nanocomposites exhibited excellent mechanical properties (e.g. tensile strength, Young's modulus and stiffness) and antimicrobial activities. Hemolysis assays indicated that blood compatibility of the polymer sample is significant. Water uptake ability of the nanocomposite materials was found to increase with increasing the proportion of PMMA-co-PHEMA. In addition, the superparamagnetic nature of the nanocomposite was observed which makes these materials suitable for magnetic therapy. This journal is © The Royal Society of Chemistry 2015. |
| Citation: | RSC Advances (2015), 5(32): 25437-25445 |
| URI: | https://doi.org/10.1039/c5ra02413g http://repository.iitr.ac.in/handle/123456789/2261 |
| Issue Date: | 2015 |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 20462069 |
| Author Scopus IDs: | 53986105300 57200575169 56324545100 57212204800 35585815900 35475516300 |
| Author Affiliations: | Bhowmick, A., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Saha, A., Department of Chemistry, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India Pramanik, N., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Banerjee, S., Department of Chemistry, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India Das, M., Department of Chemical Engineering, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Kundu, P.P., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India |
| Corresponding Author: | Kundu, P.P.; Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, India |
| Appears in Collections: | Journal Publications [CH] |
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