http://repository.iitr.ac.in/handle/123456789/2230| Title: | Fabrication of porous magnetic nanocomposites for bone tissue engineering |
| Authors: | Bhowmick A. Pramanik N. Mitra T. Gnanamani A. Das M. Kundu, Patit Paban |
| Published in: | New Journal of Chemistry |
| Abstract: | Here, the fabrication and characterization of porous magnetic nanocomposites was carried out via the blending of chitosan, polyethylene glycol and nano-hydroxyapatite-Fe3O4. Scanning electron microscope images revealed a highly interconnected macro- and micro-porous structure. These nanocomposites showed good water uptake abilities and have good antimicrobial properties. The tensile strengths of these nanocomposites were enhanced significantly compared to previously reported results, after the addition of nano-Fe3O4. Moreover, these nanocomposites could be applied for magnetic therapy as this material exhibited superparamagnetic properties. Finally, these nanocomposites were good supports for human osteoblast-like MG-63 cells' growth, attachment and proliferation and they showed good cytocompatibility. No negative effect on the MG-63 cells was observed, suggesting that these nanocomposites have great potential to be applied for bone regeneration. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. |
| Citation: | New Journal of Chemistry (2016), 41(1): 190-197 |
| URI: | https://doi.org/10.1039/C6NJ03358J http://repository.iitr.ac.in/handle/123456789/2230 |
| Issue Date: | 2016 |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 11440546 |
| Author Scopus IDs: | 53986105300 56324545100 39863189900 6602667464 35585815900 35475516300 |
| Author Affiliations: | Bhowmick, A., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Pramanik, N., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Mitra, T., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Gnanamani, A., Microbiology Division, CSIR-Central Leather Research Institute, Adyar, Chennai, Tamil Nadu 600020, India Das, M., Department of Chemical Engineering, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India Kundu, P.P., Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata, 700009, India, Department of Chemical Engineering, Indian Institute of Technology, Roorkee, 247667, India |
| Corresponding Author: | Kundu, P.P.; Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, India; email: ppk923@yahoo.com |
| Appears in Collections: | Journal Publications [CH] |
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