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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/2201
Title: Modified bacterial cellulose based self-healable polyeloctrolyte film for wound dressing application
Authors: Khamrai M.
Banerjee S.L.
Kundu, Patit Paban
Published in: Carbohydrate Polymers
Abstract: In this investigation, we prepare a self-healable polyelectrolyte film via crosslinking the cationically charged chitosan (Cts) with anionically modified bacterial cellulose (BC), which is a green source of nano-filler. This polyelectrolyte film is able to show dynamic self-healing activity at physiological pH condition via adapting ionic interaction, a state of non-covalent bond. BC was prepared using Glucanoacetobacter xylinus (MTCC7795) bacteria and after that its surface was modified with anionic poly(acrylic acid) using “grafting from” technique. It was observed that the notch (single and multiple) created over the composite film was disappeared by showing vibrant diffusion and ionic interlocking in contact with buffer solution having physiological pH. The XTT assay revealed that the composite film is non-toxic in nature and it was witnessed that the composite film was capable of delivering curcumin, a hydrophobic drug that has an ability to show antimicrobial activity and wound healing capability. © 2017 Elsevier Ltd
Citation: Carbohydrate Polymers (2017), 174(): 580-590
URI: https://doi.org/10.1016/j.carbpol.2017.06.094
http://repository.iitr.ac.in/handle/123456789/2201
Issue Date: 2017
Publisher: Elsevier Ltd
Keywords: Antimicrobial activity
Bacterial cellulose
Chitosan
Curcumin
Self-healing
Wound healing
ISSN: 1448617
Author Scopus IDs: 56641668300
56424674800
35475516300
Author Affiliations: Khamrai, M., Advanced Polymer Laboratory, Department of Polymer Science & Technology, University of Calcutta, 92 A. P. C. Road, Kolkata, 700009, India
Banerjee, S.L., Advanced Polymer Laboratory, Department of Polymer Science & Technology, University of Calcutta, 92 A. P. C. Road, Kolkata, 700009, India
Kundu, P.P., Advanced Polymer Laboratory, Department of Polymer Science & Technology, University of Calcutta, 92 A. P. C. Road, Kolkata, 700009, India, Department of Chemical Engineering, Indian Institute of Technology (IIT), Roorkee, Uttarakhand, India
Corresponding Author: Kundu, P.P.; Advanced Polymer Laboratory, Department of Polymer Science & Technology, University of Calcutta, 92 A. P. C. Road, India; email: ppk923@yahoo.com
Appears in Collections:Journal Publications [CH]

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