http://repository.iitr.ac.in/handle/123456789/20802| Title: | Light-induced metal-free transformations of unactivated pyridotriazoles |
| Authors: | Zhang Z. Yadagiri, Dongari Gevorgyan V. |
| Published in: | Chemical Science |
| Abstract: | A highly efficient and practical method for incorporation of the arylmethylpyridyl moiety into diverse molecules has been developed. This method features the transition metal-free light-induced room temperature transformation of pyridotriazoles into pyridyl carbenes, which are capable of smooth arylation, X-H insertion, and cyclopropanation reactions. The synthetic usefulness of the developed method was illustrated in a facile synthesis of biologically active molecules. © The Royal Society of Chemistry 2019. |
| Citation: | Chemical Science, 10(36): 8399-8404 |
| URI: | https://doi.org/10.1039/c9sc02448d http://repository.iitr.ac.in/handle/123456789/20802 |
| Issue Date: | 2019 |
| Publisher: | Royal Society of Chemistry |
| Keywords: | Molecules Transition metals Arylations Biologically active molecules Carbenes Cyclopropanation reaction Facile synthesis Light-induced Metal free Practical method Synthesis (chemical) |
| ISSN: | 20416520 |
| Author Scopus IDs: | 57211075589 55875148200 7003570939 |
| Author Affiliations: | Zhang, Z., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States Yadagiri, D., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States Gevorgyan, V., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States |
| Funding Details: | We thank the National Institutes of Health (GM120281) and National Science Foundation (CHE-1663779) for the nancial support of this work. National Science Foundation, NSF: 1663779, CHE-1663779; National Institutes of Health, NIH: GM120281 |
| Corresponding Author: | Gevorgyan, V.; Department of Chemistry, 845 W. Taylor St., United States; email: vlad@utdallas.edu |
| Appears in Collections: | Journal Publications [CY] |
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