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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/20802
Title: Light-induced metal-free transformations of unactivated pyridotriazoles
Authors: Zhang Z.
Yadagiri, Dongari
Gevorgyan V.
Published in: Chemical Science
Abstract: A highly efficient and practical method for incorporation of the arylmethylpyridyl moiety into diverse molecules has been developed. This method features the transition metal-free light-induced room temperature transformation of pyridotriazoles into pyridyl carbenes, which are capable of smooth arylation, X-H insertion, and cyclopropanation reactions. The synthetic usefulness of the developed method was illustrated in a facile synthesis of biologically active molecules. © The Royal Society of Chemistry 2019.
Citation: Chemical Science, 10(36): 8399-8404
URI: https://doi.org/10.1039/c9sc02448d
http://repository.iitr.ac.in/handle/123456789/20802
Issue Date: 2019
Publisher: Royal Society of Chemistry
Keywords: Molecules
Transition metals
Arylations
Biologically active molecules
Carbenes
Cyclopropanation reaction
Facile synthesis
Light-induced
Metal free
Practical method
Synthesis (chemical)
ISSN: 20416520
Author Scopus IDs: 57211075589
55875148200
7003570939
Author Affiliations: Zhang, Z., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States
Yadagiri, D., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States
Gevorgyan, V., Department of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, United States, Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 W Campbell RD, Richardson, TX 75080, United States
Funding Details: We thank the National Institutes of Health (GM120281) and National Science Foundation (CHE-1663779) for the nancial support of this work. National Science Foundation, NSF: 1663779, CHE-1663779; National Institutes of Health, NIH: GM120281
Corresponding Author: Gevorgyan, V.; Department of Chemistry, 845 W. Taylor St., United States; email: vlad@utdallas.edu
Appears in Collections:Journal Publications [CY]

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