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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/20799
Title: Denitrogenative Transformations of Pyridotriazoles and Related Compounds: Synthesis of N-Containing Heterocyclic Compounds and beyond
Authors: Yadagiri, Dongari
Rivas M.
Gevorgyan V.
Published in: Journal of Organic Chemistry
Abstract: The high demand for new and efficient routes toward synthesis of nitrogen-containing heterocyclic scaffolds has inspired organic chemists to discover several methodologies over recent years. This Perspective highlights one standout approach, which involves the use of pyridotriazoles and related compounds in denitrogenative transformations. Readily available pyridotriazoles undergo ring-chain isomerization to produce uniquely reactive α-diazoimines. Such reactivity, enabled by metal catalysts, additives, or visible-light irradiation, can be applied in transannulation, insertion, cyclopropanation, and many other transformations. © 2020 American Chemical Society.
Citation: Journal of Organic Chemistry, 85(17): 11030-11046
URI: https://doi.org/10.1021/acs.joc.0c01652
http://repository.iitr.ac.in/handle/123456789/20799
Issue Date: 2020
Publisher: American Chemical Society
Keywords: Additives
Catalysts
Organic compounds
Scaffolds
Chain isomerization
Cyclopropanation
Heterocyclic compound
High demand
Metal catalyst
Related compounds
Transannulation
Visible-light irradiation
Synthesis (chemical)
benzylamine derivative
copper
heterocyclic compound
indole derivative
Lewis acid
nitrogen
rhodium
triazole derivative
annulation reaction
biotransformation
catalysis
cyclization
cycloaddition
cyclopropanation
denitrogenative transformation
electron
electron transport
electrophilicity
irradiation
isomerization
nucleophilicity
oxidation
photolysis
Review
ring opening
synthesis
ISSN: 223263
Author Scopus IDs: 55875148200
57200315913
7003570939
Author Affiliations: Yadagiri, D., Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 West Campbell Road, Richardson, TX 75080-3021, United States
Rivas, M., Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 West Campbell Road, Richardson, TX 75080-3021, United States
Gevorgyan, V., Department of Chemistry and Biochemistry, University of Texas at Dallas, 800 West Campbell Road, Richardson, TX 75080-3021, United States
Funding Details: We thank the National Institute of Health (GM120281), National Science Foundation (CHE-1955663), and Welch Foundation (Chair, AT-0041) for financial support. National Science Foundation, NSF: 1955663, CHE-1955663; National Institutes of Health, NIH: GM120281; Welch Foundation: AT-0041
Corresponding Author: Gevorgyan, V.; Department of Chemistry and Biochemistry, 800 West Campbell Road, United States; email: vlad@utdallas.edu
Appears in Collections:Journal Publications [CY]

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