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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/20600
Title: A Green, Solvent-Free, Microwave-Assisted, High-Yielding YbCl3Catalyzed Deprotection of THP/MOM/Ac/Ts Ethers of Chalcone Epoxide and 2′-Aminochalcone and Their Sequel Cyclization
Authors: Kumar S.
Verma N.
Parveen I.
Ahmed, Naseem
Published in: Journal of Heterocyclic Chemistry
Abstract: Under microwave and solvent-free conditions, YbCl3efficiently catalyzed the deprotection of tetrahydropyran-2-yl, methoxymethyl (MOM), acetyl, and tosyl groups and sequel cyclization of chalcone epoxide to 2-hydroxyindanone and 2′-aminochalcone to aza-flavanone. The reaction afforded the products in excellent yield (78–99%) at 850 W microwave heating within 1–5 min under eco-friendly conditions. The merits of the presented protocol include high yield, use of microwave irradiation, solvent-free condition, catalyst reusability, and no need for purification with column chromatography. The present method is very much milder but more advanced than those reported earlier. © 2015 HeteroCorporation
Citation: Journal of Heterocyclic Chemistry, 53(6): 2111-2122
URI: https://doi.org/10.1002/jhet.2517
http://repository.iitr.ac.in/handle/123456789/20600
Issue Date: 2016
Publisher: HeteroCorporation
Keywords: acetic acid derivative
chalcone derivative
ether derivative
flavanone derivative
methyl group
tetrahydropyran derivative
ytterbium
Article
catalysis
catalyst
cyclization
deprotection reaction
microwave irradiation
quantum yield
reaction analysis
ISSN: 0022152X
Author Scopus IDs: 56167238700
56666842900
56561070300
7401846814
Author Affiliations: Kumar, S., Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, 247 667, India
Verma, N., Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, 247 667, India
Parveen, I., Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, 247 667, India
Ahmed, N., Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, 247 667, India
Corresponding Author: Kumar, S.; Department of Chemistry, India; email: sumitdcy@iitr.ac.in
Appears in Collections:Journal Publications [CY]

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