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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/1621
Title: Synthesis, anti-inflammatory and anticancer activity evaluation of some mono-And bis-Schiff's bases
Authors: Sondhi S.M.
Arya S.
Rani R.
Kumar N.
Roy P.
Published in: Medicinal Chemistry Research
Abstract: Several mono-Schiff's bases (3a-i) and bis-Schiff's bases (5a-f) were synthesized using microwave irradiation technique (3a-h, 5a-c) and by simply grinding at room temperature for a few minutes (3i, 5d-f). All these compounds were characterized by spectroscopic means and elemental analysis. They were screened for anti-inflammatory and anticancer activities (against five human cancer cell lines). Compound 5f exhibited good anti-inflammatory and compounds 3f, 5a-f exhibited good anticancer activity. © Springer Science+Business Media, LLC 2011.
Citation: Medicinal Chemistry Research (2012), 21(11): 3620-3628
URI: https://doi.org/10.1007/s00044-011-9899-3
http://repository.iitr.ac.in/handle/123456789/1621
Issue Date: 2012
Keywords: Anti-inflammatory
Anticancer evaluation
Bis-Schiff's bases
Schiff's bases
ISSN: 10542523
Author Scopus IDs: 7006090710
54402273600
16507511200
57192281884
35509207200
Author Affiliations: Sondhi, S.M., Department of Chemistry, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India
Arya, S., Department of Chemistry, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India
Rani, R., Department of Chemistry, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India
Kumar, N., Department of Biotechnology, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India
Roy, P., Department of Biotechnology, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India
Funding Details: Acknowledgments We thank the technical staff of Chemistry Department, IIT Roorkee, for their assistance in spectroscopic studies and elemental analysis and to Mr. Rakesh Kumar (Integral Biosciences Ltd. Noida) for helping to use microwave reactor. One of the authors Ms. Surbhi Arya (JRF-NET) thanks to CSIR, New Delhi, for financial assistance.
Corresponding Author: Sondhi, S.M.; Department of Chemistry, Indian Institute of Technology, Roorkee, Uttrakhand 247667, India; email: sondifcy@iitr.ernet.in
Appears in Collections:Journal Publications [BT]

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