Skip navigation
Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/1551
Title: Characterization and in vitro biocompatibility study of Ti-Si-N nanocomposite coatings developed by using physical vapor deposition
Authors: Trivedi P.
Gupta P.
Srivastava S.
Jayaganthan R.
Chandra R.
Roy, Partha
Published in: Applied Surface Science
Abstract: Amongst the Ti alloys used as orthopedic implant materials, Ti6Al4V is one of the widely used alloys. Magnetron sputtering was used to deposit nanocomposite coating of Ti-Si-N on the Ti6Al4V substrate at different power and then the coating structure and surface properties were characterized through contact angle measurement, X-ray diffraction (XRD), scanning electron microscopy (SEM), and atomic force microscopy (AFM). In vitro biocompatibility of the coatings was assessed by using mouse bone marrow mesenchymal stem cells (mBMMSC). Antibacterial studies were performed using Escherichia coli (E. coli) microorganisms. The osteogenic differentiation was also carried out in order to get gene expressions. The AFM results confirmed that the coatings deposited at 120 W was smoother as compared to other coatings developed at different power, along with optimum contact angle, also these coatings showed good antibacterial results. The fluorescent and viability results of 120 W sample confirmed their good biocompatibility as compared to the coatings deposited 20, 40, 60, and 100 W power. Hence, the coating deposited at 120 W exhibit desirable microstructural characteristics beneficial for surface modification of orthopedic implants. © 2013 Elsevier B.V.
Citation: Applied Surface Science (2014), 293(): 143-150
URI: https://doi.org/10.1016/j.apsusc.2013.12.119
http://repository.iitr.ac.in/handle/123456789/1551
Issue Date: 2014
Publisher: Elsevier B.V.
Keywords: Biocompatibility
Characterisations
Coatings
Sputtering
ISSN: 1694332
Author Scopus IDs: 55999013600
57206494195
40262604000
6602183770
56591551200
35509207200
Author Affiliations: Trivedi, P., Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India
Gupta, P., Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India
Srivastava, S., Department of Biotechnology, Indian Institute of Technology, Roorkee, India
Jayaganthan, R., Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, India, Indian Institute of Technology Roorkee, Department of Metallurgical and Materials Engineering, Roorkee, India
Chandra, R., Nanoscience Laboratory, Institute Instrumentation Centre, Indian Institute of Technology, Roorkee, India
Roy, P., Department of Biotechnology, Indian Institute of Technology, Roorkee, India
Corresponding Author: Jayaganthan, R.; Indian Institute of Technology Roorkee, Department of Metallurgical and Materials Engineering, Roorkee, India; email: rjayafmt@iitr.ernet.in
Appears in Collections:Journal Publications [BT]

Files in This Item:
There are no files associated with this item.
Show full item record


Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.