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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/15352
Title: Spatial correlation of trace elements with morphological features of atherosclerotic plaques
Authors: Roijers R.B.
Dutta, Raj Kumar
Mutsaers P.H.A.
Gijbels M.J.J.
De Winther M.P.J.
De Goeij J.J.M.
Van Der Vusse G.J.
Jaksic M.
Radovic I.B.
Medunic Z.
Published in: Proceedings of Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Abstract: A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy. © 2005 Elsevier B.V. All rights reserved.
Citation: Proceedings of Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, (2005), 239- 244
URI: https://doi.org/10.1016/j.nimb.2005.01.064
http://repository.iitr.ac.in/handle/123456789/15352
Issue Date: 2005
Keywords: Atherosclerosis
Histology
Nuclear microprobe
PIXE
Region of interest
ISSN: 0168583X
Author Scopus IDs: 12752158900
47161194700
7003294979
35512381800
6701795528
7005529444
7102878246
Author Affiliations: Roijers, R.B., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands
Dutta, R.K., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands
Mutsaers, P.H.A., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands
Gijbels, M.J.J., Interfaculty Reactor Institute, Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands
De Winther, M.P.J., Interfaculty Reactor Institute, Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands
De Goeij, J.J.M., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands, Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, P.O. Box 616, 6200 MD Maastricht, Netherlands
Van Der Vusse, G.J., Department of Molecular Genetics, Maastricht University, P.O. Box 616, 6200 MD Maastricht, Netherlands
Funding Details: This research work is funded by FOM (Project number 00PMT13). The authors’ thank’s go to Paul Bomans, Hans Duimel and Peter Frederik for their assistance in sample preparation.
Corresponding Author: Roijers, R.B.; Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands; email: r.b.roijers@tue.nl
Appears in Collections:Conference Publications [CY]

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