http://repository.iitr.ac.in/handle/123456789/15352| Title: | Spatial correlation of trace elements with morphological features of atherosclerotic plaques |
| Authors: | Roijers R.B. Dutta, Raj Kumar Mutsaers P.H.A. Gijbels M.J.J. De Winther M.P.J. De Goeij J.J.M. Van Der Vusse G.J. Jaksic M. Radovic I.B. Medunic Z. |
| Published in: | Proceedings of Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms |
| Abstract: | A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy. © 2005 Elsevier B.V. All rights reserved. |
| Citation: | Proceedings of Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, (2005), 239- 244 |
| URI: | https://doi.org/10.1016/j.nimb.2005.01.064 http://repository.iitr.ac.in/handle/123456789/15352 |
| Issue Date: | 2005 |
| Keywords: | Atherosclerosis Histology Nuclear microprobe PIXE Region of interest |
| ISSN: | 0168583X |
| Author Scopus IDs: | 12752158900 47161194700 7003294979 35512381800 6701795528 7005529444 7102878246 |
| Author Affiliations: | Roijers, R.B., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands Dutta, R.K., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands Mutsaers, P.H.A., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands Gijbels, M.J.J., Interfaculty Reactor Institute, Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands De Winther, M.P.J., Interfaculty Reactor Institute, Delft University of Technology, Mekelweg 15, 2629 JB Delft, Netherlands De Goeij, J.J.M., Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands, Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, P.O. Box 616, 6200 MD Maastricht, Netherlands Van Der Vusse, G.J., Department of Molecular Genetics, Maastricht University, P.O. Box 616, 6200 MD Maastricht, Netherlands |
| Funding Details: | This research work is funded by FOM (Project number 00PMT13). The authors’ thank’s go to Paul Bomans, Hans Duimel and Peter Frederik for their assistance in sample preparation. |
| Corresponding Author: | Roijers, R.B.; Cyclotron Laboratory, Department of Applied Physics, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, Netherlands; email: r.b.roijers@tue.nl |
| Appears in Collections: | Conference Publications [CY] |
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