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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/1531
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dc.contributor.authorKumar S.-
dc.contributor.authorKumar N.-
dc.contributor.authorRoy, Partha-
dc.contributor.authorSondhi S.M.-
dc.date.accessioned2020-09-30T11:39:16Z-
dc.date.available2020-09-30T11:39:16Z-
dc.date.issued2014-
dc.identifier.citationMedicinal Chemistry Research (2014), 23(9): 3953-3969-
dc.identifier.issn10542523-
dc.identifier.urihttps://doi.org/10.1007/s00044-014-0969-1-
dc.identifier.urihttp://repository.iitr.ac.in/handle/123456789/1531-
dc.description.abstractPiperazine dione derivatives (1a-j) on condensation with 2,6-pyridine dicarboxylic acid (2x), 3,5-pyridine dicarboxylic acid (2y) and 2,5-thiophene dicarboxylic acid (2z) gave corresponding heterocyclic compounds 3ax-3jz in excellent yields. All the newly synthesized compounds were fully characterized by spectroscopic means and elemental analysis. On screening for anti-inflammatory and for in vitro anticancer activity, compounds 3bx, 3cx, 3dx, and 3ex exhibited good anti-inflammatory activity, whereas compounds 3ay, 3az, 3cz, 3dx, 3ez, 3fx, 3gx, and 3hz exhibited good anticancer activity. © Springer Science+Business Media 2014.-
dc.language.isoen_US-
dc.publisherBirkhauser Boston-
dc.relation.ispartofMedicinal Chemistry Research-
dc.subject2,6-Dioxopiperazine derivatives-
dc.subjectAnti-inflammatory-
dc.subjectAnticancer-
dc.subjectSynthesis-
dc.titleEfficient synthesis of heterocyclic compounds derived from 2,6-dioxopiperazine derivatives and their evaluation for anti-inflammatory and anticancer activities-
dc.typeArticle-
dc.scopusid57216459762-
dc.scopusid57201756182-
dc.scopusid35509207200-
dc.scopusid7006090710-
dc.affiliationKumar, S., Department of Chemistry, Indian Institute of Technology-Roorkee, Roorkee, 247667, India-
dc.affiliationKumar, N., Department of Biotechnology, Indian Institute of Technology-Roorkee, Roorkee, 247667, India-
dc.affiliationRoy, P., Department of Biotechnology, Indian Institute of Technology-Roorkee, Roorkee, 247667, India-
dc.affiliationSondhi, S.M., Department of Chemistry, Indian Institute of Technology-Roorkee, Roorkee, 247667, India-
dc.description.fundingAcknowledgments We are thankful to technical staff of the Chemistry Department, I. I. T. Roorkee, for spectroscopic studies and elemental analysis. Thanks also due to Head I.I.C. for providing NMR facility. Mr. Sandeep Kumar is thankful to MHRD New Delhi for financial assistance.-
dc.description.correspondingauthorSondhi, S.M.; Department of Chemistry, Indian Institute of Technology-RoorkeeIndia-
Appears in Collections:Journal Publications [BT]

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