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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/1510
Title: Silver-nanoparticle-Incorporated composite nanofibers for potential wound-dressing applications
Authors: Dubey P.
Bhushan B.
Sachdev A.
Matai I.
Uday Kumar S.
Gopinath, Packirisamy
Published in: Journal of Applied Polymer Science
Abstract: The aim of this study was to develop stable and porous poly(ethylene oxide) (PEO)-polycaprolactone blended and silver nanoparticle (Ag NP) incorporated composite nanofiber scaffolds as antibacterial wound dressings. A facile approach for the in situ synthesis of Ag NPs was explored. In this synthesis method, N,N-dimethylformamide (DMF) was used as a solvent; it also acted as reducing agent for Ag NP formation. The stabilization of Ag NPs in the fibers was accomplished by PEO, which in turn acted as a reducing agent along with DMF. The successful synthesis of crystalline Ag NPs was confirmed by various characterization techniques. Thermogravimetric analysis, wettability, and surface roughness analysis of the nanofibers were done to examine the suitability of the scaffold for wound dressing. The as-synthesized composite nanofibers possessed good roughness, wettability, and antibacterial potential against recombinant green fluorescent proteins expressing antibiotic-resistant Escherichia coli. Thus, the nanofiber scaffold fabricated by this approach could serve as an ideal wound dressing. © 2015 Wiley Periodicals, Inc.
Citation: Journal of Applied Polymer Science(2015), 132(35): -
URI: https://doi.org/10.1002/app.42473
http://repository.iitr.ac.in/handle/123456789/1510
Issue Date: 2015
Publisher: John Wiley and Sons Inc.
Keywords: applications
biomedical applications
composites
electrospinning
fibers
ISSN: 218995
Author Scopus IDs: 56830630100
55553734432
55853618300
55580357700
55991841000
56242963200
Author Affiliations: Dubey, P., Nanobiotechnology Laboratory, Centre for Nanotechnology, Indian Institute of Technology Roorkee, Uttarakhand, 247667, India
Bhushan, B., Nanobiotechnology Laboratory, Centre for Nanotechnology, Indian Institute of Technology Roorkee, Uttarakha
Corresponding Author: Gopinath, P.; Nanobiotechnology Laboratory, Centre for Nanotechnology, Indian Institute of Technology RoorkeeIndia
Appears in Collections:Journal Publications [BT]

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