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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/1445
Title: Cold atmospheric pressure (CAP) plasma assisted tailoring of LDPE film surfaces for enhancement of adhesive and cytocompatible properties: Influence of operating parameters
Authors: Pandiyaraj K.N.
RamKumar M.C.
Arun Kumar A.
Padmanabhan P.V.A.
Deshmukh R.R.
Bendavid A.
Su P.-G.
Sachdev A.
Gopinath, Packirisamy
Abstract: Low density polyethylene (LDPE) plays a vital role in tissue engineering application because of its superior bulk properties. However, the cell affinity is one of the significant factors in determining the cell compatibility of polymers which depends on the surface properties such as hydrophilicity, surface chemistry and morphology. Due to intrinsic poor surface properties, the cell affinity is one of the major deterrents of LDPE films in biomedical applications. Hence, in the present investigation we discuss the influence of operating parameters such as applied potential, exposure time and type of plasma processing gases on the improvement of surface and cell compatible properties of the LDPE film using cold atmospheric pressure (CAP) plasma. The surface chemistry and hydrophilicity of the LDPE films were examined using X-ray photoelectron spectroscopy (XPS), contact angle (CA) respectively. Further, surface energy (SE) of the LDPE films were estimated from CA data by Fowke's approximation method. The quantification of topographical changes on the surface of LDPE films was carried out by atomic force microscopy (AFM). Adhesive strength of the surface modified films was analyzed by T-peel and lap shear tests. Finally, in vitro cytocompatibility studies of the surface modified LDPE films were carried out using NIH3T3 (mouse embryonic fibroblast) cells. The results obtained from various characterization techniques evidently revealed that CAP plasma treatment enhanced the surface properties (hydrophilicity, surface morphology and surface chemistry) of the LDPE films. These physico-chemical changes induced by the CAP plasma treatment facilitates the improvement in adhesive strength as well as adhesion and proliferation of cells on the surface of LDPE films. © 2016 Elsevier Ltd. All rights reserved.
Citation: (2016), 130(): 34-47
URI: https://doi.org/10.1016/j.vacuum.2016.04.029
http://repository.iitr.ac.in/handle/123456789/1445
Issue Date: 2016
Publisher: Elsevier Ltd
Keywords: Adhesive strength
CAP plasma
Cell compatibility
Hydrophilicity
LDPE films
ISSN: 0042207X
Author Scopus IDs: 23101126600
18837743900
57188927532
57210690847
7005934292
6701783313
35294033500
55853618300
56242963200
Author Affiliations: Pandiyaraj, K.N., Surface Engineering Laboratory, Department of Physics, Sri Shakthi Institute of Engineering and Technology, Coimbatore, 641062, India
RamKumar, M.C., Surface Engineering Laboratory, Department of Physics, Sri Shakthi Institute of Engine
Funding Details: One of the authors (K.N) would like to express his sincere gratitude to Department of Atomic Energy and Board of Research in Nuclear Science (DAE-BRNS) Government of India for providing the financial support (Ref: 34/14/05/2014-BRNS/2124 ).
Corresponding Author: Pandiyaraj, K.N.; Surface Engineering Laboratory, Department of Physics, Sri Shakthi Institute of Engineering and TechnologyIndia; email: dr.knpr@gmail.com
Appears in Collections:Journal Publications [BT]

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