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Please use this identifier to cite or link to this item: http://repository.iitr.ac.in/handle/123456789/12926
Title: Microstructure, mechanical properties, and in vitro biocompatibility of spark plasma sintered hydroxyapatite-aluminum oxide-carbon nanotube composite
Authors: Kalmodia S.
Goenka S.
Laha T.
Lahiri, Debrupa
Basu B.
Balani K.
Published in: Materials Science and Engineering C
Abstract: In the present work, HA reinforced with Al2O3 and multiwalled carbon nanotubes (CNTs) is processed using spark plasma sintering (SPS). Vickers micro indentation and nanoindentation of the samples revealed contrary mechanical properties (hardness of 4.0, 6.1, and 4.4 GPa of HA, HA-Al2O3 and HA-Al2O3-CNT samples at bulk scale, while that of 8.0, 9.0, and 7.0 GPa respectively at nanoscale), owing to the difference in the interaction of the indenter with the material at two different length scales. The addition of Al2O3 reinforcement has been shown to enhance the indentation fracture toughness of HA matrix from 1.18 MPa m1/2 to 2.07 MPa m1/2. Further CNT reinforcement has increased the fracture toughness to 2.3 times (2.72 MPa m 1/2). In vitro biocompatibility of CNT reinforced HA-Al 2O3 composite has been evaluated using MTT assay on mouse fibroblast L929 cell line. Cell adhesion and proliferation have been characterized using scanning electron microscopy (SEM), and have been quantified using UV spectrophotometer. The combination of cell viability data as well as microscopic observations of cultured surfaces suggests that SPS sintered HA-Al2O3-CNT composites exhibit the ability to promote cell adhesion and proliferation on their surface and prove to be promising new biocompatible materials. © 2010 Elsevier B.V.
Citation: Materials Science and Engineering C (2010), 30(8): 1162-1169
URI: https://doi.org/10.1016/j.msec.2010.06.009
http://repository.iitr.ac.in/handle/123456789/12926
Issue Date: 2010
Keywords: Alumina (Al2O3)
Biocompatibility
Carbon nanotubes (CNTs)
Fracture toughness
Hydroxyapatite (HA)
Spark plasma sintering (SPS)
ISSN: 9284931
Author Scopus IDs: 26428237600
57197076734
6602771508
26326345700
35576893400
8218235100
Author Affiliations: Kalmodia, S., Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Kanpur-208016, India
Goenka, S., Department of Metallurgical Engineering, Punjab Engineering College, D.U. Chandigarh-160012, India, Department of Chemical and Materials Engineering, University of Cincinnati, OH 45221, United States
Laha, T., Department of Metallurgical and Materials Engineering, Indian Institute of Technology Kharagpur, Kharagpur-721302, India, Department of Chemical Engineering and Materials Science, University of California Davis, CA 95616, United States
Lahiri, D., Department of Mechanical and Materials Engineering, Florida International University, Miami, FL 33174, United States
Basu, B., Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Kanpur-208016, India
Balani, K., Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Kanpur-208016, India
Corresponding Author: Balani, K.; Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Kanpur-208016, India; email: kbalani@iitk.ac.in
Appears in Collections:Journal Publications [MT]

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