http://repository.iitr.ac.in/handle/123456789/12630| Title: | Carbon nanotube reinforced polylactide-caprolactone copolymer: Mechanical strengthening and interaction with human osteoblasts in vitro |
| Authors: | Lahiri, Debrupa Rouzaud F. Namin S. Keshri A.K. Valdas J.J. Kos L. Tsoukias N. Agarwal A. |
| Published in: | ACS Applied Materials and Interfaces |
| Abstract: | This study proposes the use of carbon nanotubes (CNTs) as reinforcement to enhance the mechanical properties of a polylactide-caprolactone copolymer (PLC) matrix. Biological interaction of PLC-CNT composites with human osteoblast cells is also investigated. Addition of 2 wt % CNT shows very uniform dispersion in the copolymer matrix, whereas 5 wt % CNT shows severe agglomeration and high porosity. PLC-2 wt % CNT composite shows an improvement in the mechanical properties with an increase in the elastic modulus by 100% and tensile strength by 160%, without any adverse effect on the ductility up to 240% elongation. An in vitro biocompatibility study on the composites shows an increase in the viability of human osteoblast cells compared to the PLC matrix, which is attributed to the combined effect of CNT content and surface roughness of the composite films. © 2009 American Chemical Society. |
| Citation: | ACS Applied Materials and Interfaces (2009), 1(11): 2470-2476 |
| URI: | https://doi.org/10.1021/am900423q http://repository.iitr.ac.in/handle/123456789/12630 |
| Issue Date: | 2009 |
| Keywords: | biodegradable scaffold carbon nanotube osteoblast PLA-PCL copolymer strengthening viability |
| ISSN: | 19448244 |
| Author Scopus IDs: | 26326345700 6602452354 26635765100 35205917600 55513256500 7004015655 6603120620 7401480913 |
| Author Affiliations: | Lahiri, D., Department of Mechanical and Materials Engineering, Florida International University, Miami, FL 33174, United States Rouzaud, F., Department of Biological Sciences, Florida International University, Miami, FL 33174, United States Namin, S., Department of Biomedical Engineering, Florida International University, Miami, FL 33174, United States Keshri, A.K., Department of Mechanical and Materials Engineering, Florida International University, Miami, FL 33174, United States Valdés, J.J., Department of Biological Sciences, Florida International University, Miami, FL 33174, United States Kos, L., Department of Biological Sciences, Florida International University, Miami, FL 33174, United States Tsoukias, N., Department of Biomedical Engineering, Florida International University, Miami, FL 33174, United States Agarwal, A., Department of Mechanical and Materials Engineering, Florida International University, Miami, FL 33174, United States |
| Corresponding Author: | Agarwal, A.; Department of Mechanical and Materials Engineering, Florida International University, Miami, FL 33174, United States |
| Appears in Collections: | Journal Publications [MT] |
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