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Title: A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound
Authors: Araki T.
Ikeda N.
Dey N.
Chakraborty S.
Saba L.
Kumar D.
Godia E.C.
Jiang X.
Gupta A.
Radeva P.
Laird J.R.
Nicolaides A.
Suri J.S.
Published in: Computer Methods and Programs in Biomedicine
Abstract: In IVUS imaging, constant linear velocity and a constant angular velocity of 1800. rev/min causes displacement of the calcium in subsequent image frames. To overcome this error in intravascular ultrasound video, IVUS image frames must be registered prior to the lesion quantification. This paper presents a comprehensive comparison of four registration methods, namely: Rigid, Affine, B-Splines and Demons on five set of calcium lesion quantification parameters namely: (i) the mean lesion area, (ii) mean lesion arc, (iii) mean lesion span, (iv) mean lesion length, and (v) mean lesion distance from catheter.Using our IRB approved data of 100 patient volumes, our results shows that all four registrations showed a decrease in five calcium lesion parameters as follows: for Rigid registration, the values were: 4.92%, 5.84%, 5.89%, 5.27%, and 4.57%, respectively, for Affine registration the values were: 6.06%, 6.51%, 7.28%, 6.50%, and 5.94%, respectively, for B-Splines registration the values were: 7.35%, 8.03%, 9.54%, 8.18%, and 7.62%, respectively, and for Demons registration the five parameters were 7.32%, 8.02%, 10.11%, 7.94%, and 8.92% respectively.The relative overlap of identified lesions decreased by 5.91% in case of Rigid registration, 6.23% in case of Affine registration, 4.48% for Demons registration, whereas it increased by 3.05% in case of B-Splines registration. Rigid and Affine transformation-based registration took only 0.1936 and 0.2893. s per frame, respectively. Demons and B-Splines framework took only 0.5705 and 0.9405. s per frame, respectively, which were significantly slower than Rigid and Affine transformation based image registration. © 2014 Published by Elsevier Ireland Ltd.
Citation: Computer Methods and Programs in Biomedicine (2015), 118(2): 158-172
Issue Date: 2015
Publisher: Elsevier Ireland Ltd
Keywords: AtheroEdgeâ„¢
ISSN: 1692607
Author Scopus IDs: 35557901200
Author Affiliations: Araki, T., Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, 2-17-6 Ohashi, Meguro-ku, Tokyo, Japan
Ikeda, N., Division of Cardiovascular Medicine, Centre for Global Health and Medicine (NCGM), 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan
Dey, N., Point of Care Devices, Global Biomedical Technologies, Inc., Roseville, CA, United States
Chakraborty, S., Point of Care Devices, Global Biomedical Technologies, Inc., Roseville, CA, United States
Saba, L., Azienda Ospedaliero Universitaria (A.O.U.) di Cagliari - Polo di Monserrato, Università di Cagliari, S.s. 554 Monserrato, Cagliari, 09045, Italy
Kumar, D., Stoke Screening and Monitoring Division, AtheroPoint LLC, Roseville, CA, United States
Godia, E.C., IMIM - Hospital del Mar, Passeig Marítim 25-29, Barcelona, Spain
Jiang, X., Department of Computer Science, University of Münster, Münster, Germany
Gupta, A., Department of Radiology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, United States
Radeva, P., MILab, CVC, University of Barcelona, Barcelona, Spain, Applied Mathematics and Analysis Department, University of Barcelona, Barcelona, Spain
Laird, J.R., UC Davis Vascular Center, University of California, Davis, CA, United States
Nicolaides, A., Vascular Screening and Diagnostic Centre, London, United Kingdom, Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus
Suri, J.S., Point of Care Devices, Global Biomedical Technologies, Inc., Roseville, CA, United States, Stoke Screening and Monitoring Division, AtheroPoint LLC, Roseville, CA, United States, Electrical Engineering Department (Affl.), Idaho State University, Pocatello, ID, United States
Corresponding Author: Suri, J.S.; Stoke Screening and Monitoring Division, AtheroPoint LLCUnited States
Appears in Collections:Journal Publications [ME]

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